基本介绍
肖仕
院长 博士 教授 博导
专业方向
植物低氧感知与信号转导、植物细胞自噬发生的调控机理、植物抗病虫激素信号转导
人才项目
2012年入选“国家海外高层次人才计划青年项目”，2017年获“国家杰出青年科学基金”项目资助，2019年入选国家“万人计划”科技创新领军人才
教育经历
2005-2008，香港大学，生物科学学院，博士
1995-2003，湖南农业大学，本科、硕士
工作经历
2024.04至今，中山大学，农业与生物技术学院，院长
2023.11-2024.03，中山大学，农学院，院长
2011-2023，中山大学，生命科学学院，副教授、教授、副院长
2008-2011，香港大学，生物科学学院，Post-Doctoral Fellow
2001-2005，新加坡分子与细胞生物研究院，Assistant Research Officer
科研成果
近年来在植物低氧感知与信号转导、植物细胞自噬发生的调控机理、植物抗病虫激素信号转导等方面取得了许多重要发现。在Progress in Lipid Research、Autophagy、Plant Cell、Molecular Plant、PLoS Genetics、Plant Biotechnology Journal和New Phytologist等国际权威期刊上发表SCI论文80余篇（其中ESI高被引论文6篇，特邀综述论文4篇），论文被引用6000余次，获美国和中国授权专利8项，获2021年度广东省自然科学奖二等奖（第一完成人）。
代表性论文（*通讯作者）
21. Qi H#, Wang Y#, Bao Y, Bassham BC, Chen L, Chen QF, Hou SW, Hwang I, Huang L, Lai ZB, Li FQ, Liu YL, Qiu RL, Wang H, Wang PW, Xie QJ, Zeng YL, Zhuang XH, Gao CJ*, Jiang L* and Xiao S*. (2023) Studying plant autophagy: challenges and recommended methodologies. Advanced Biotechnology 1(4): 2.
20. Fan B#, Liao K#, Wang LN, Shi LL, Zhang Y, Xu LJ, Zhou Y, Li JF, Chen YQ, Chen QF*, and Xiao S*. (2023) Calcium-dependent activation of CPK12 facilitates its cytoplasm-to-nucleus translocation to potentiate plant hypoxia sensing by phosphorylating ERF-VII transcription factors. Molecular Plant 16: 979-998. (Cover story；spotlight推荐论文).
19. Dai YS#, Liu D#, Guo W#, Liu ZX, Zhang X, Shi LL, Zhou DM, Wang LN, Kang K, Wang FZ, Zhao SS, Tan YF, Hu T, Chen W, Li P, Zhou QM, Yuan LY. Zhang Z, Chen YQ, Zhang WQ, Li J*, Yu LJ*, and Xiao S*. (2023) Poaceae-specific β-1,3;1,4-D-glucans link jasmonate signaling to OsLecRK1-mediated defense response during rice-brown planthopper interaction. Plant Biotechnology Journal 21: 1286-1300.
18. Yuan LB, Chen MX*, Wang LN, Sasidharan R, Voesenek LACJ*, and Xiao S*. (2023) Multi-stress resilience in plants recovering from submergence. Plant Biotechnology Journal 21: 466-481.
17. Xie LJ#, Wang JH#, Liu HS#, Yuan LB, Tan YF, Tan WJ, Zhou Y, Chen QF, Qi H, Li JF, Chen YQ, Qiu RL, Chen MX*, and Xiao S*. (2023) MYB30 integrates light signals with antioxidant biosynthesis to regulate plant responses during post-submergence recovery. New Phytologist 237: 2238-2254.
16. Qi H#, Lei X#, Wang Y#, Yu S, Liu T, Zhou SK, Chen JY, Chen QF, Qiu RL, Jiang LW, and Xiao S*. (2022) 14-3-3 proteins contribute to autophagy by modulating SINAT-mediated ATG13 degradation. Plant Cell 34: 4857-4876.
15. Zhou Y, Zhou DM, Yu WW, Shi LL, Lai YX, Huang LP, Chen QF, Yao N, Li JF, Xie LJ*, and Xiao S*. (2022) Phosphatidic acid modulates MPK3- and MPK6-mediated hypoxia signaling in Arabidopsis. Plant Cell 34: 889-909. (ESI高被引论文).
14. Xie LJ, Zhou Y, Chen QF*, and Xiao S*. (2021) New insights into the role of lipids in plant hypoxia responses. Progress in Lipid Research 81: 101072. (invited review)
13. Qi H, Xia FN, and Xiao S*. (2021) Autophagy in plants: physiological roles and post-translational regulation. Journal of Integrative Plant Biology 63(1):161-179. (invited review, ESI高被引论文)
12. Xia FN, Zeng BQ, Liu HS, Qi H, Xie LJ, Yu LJ, Chen QF, Li JF, Chen YQ, Jiang LW, and Xiao S*. (2020) SINAT E3 ubiquitin ligases mediate FREE1 and VPS23A degradation to modulate abscisic acid signaling. Plant Cell 32: 3290-3310.
11. Qi H#, Li J#, Xia FN, Chen JY, Lei X, Han MQ, Xie LJ, Zhou QM, and Xiao S*. (2020) Arabidopsis SINAT proteins control autophagy by mediating ubiquitylation and degradation of ATG13. Plant Cell 32: 263-284. (ESI高被引论文)
10. Liao K#, Peng YJ#, Yuan LB#, Dai YS#, Chen QF, Yu LJ, Bai MY, Zhang WQ, Xie LJ*, and Xiao S*. (2020) Brassinosteroids antagonize jasmonates-activated plant defense responses through BRI1-EMS-SUPPRESSOR1 (BES1). Plant Physiology 182: 1066-1082.
9. Zhou Y#, Tan WJ#, Xie LJ, Qi H, Yang YC, Huang LP, Lai YX, Tan YF, Zhou DM, Yu LJ, Chye ML, and Xiao S*. (2020) Polyunsaturated linolenoyl-CoA modulates ERF-VII-mediated hypoxia signaling in Arabidopsis. Journal of Integrative Plant Biology 62: 330-348.
8. Huang L#, Yu LJ#, Zhang X, Fan B, Wang FZ, Dai YS, Qi H, Zhou Y, Xie LJ, and Xiao S*. (2019) Autophagy regulates glucose-mediated root meristem activity by modulating ROS production in Arabidopsis. Autophagy 15: 407-422.
7. Tan WJ, Yang YC, Zhou Y, Huang LP, Xu L, Chen QF, Yu LJ*, and Xiao S*. (2018) Diacylglycerol acyltransferase and diacylglycerol kinase modulate triacylglycerol and phosphatidic acid production in the plant response to freezing stress. Plant Physiology 177: 1303-1318. (重点推荐论文)
6. Qi H#, Xia FN#, Xie LJ#, Yu LJ, Chen QF, Zhuang XH, Wang Q, Li F, Jiang L, Xie Q, and Xiao S*. (2017) TRAF-family proteins regulate autophagy dynamics by modulating AUTOPHAGY PROTEIN6 stability in Arabidopsis. Plant Cell 29: 890-911. (重点推荐论文)
5. Yuan LB#, Dai YS#, Xie LJ#, Yu LJ, Zhou Y, Lai YX, Yang YC, Xu L, Chen QF, and Xiao S*. (2017) Jasmonate regulates plant responses to postsubmergence reoxygenation through transcriptional activation of antioxidant synthesis. Plant Physiology 173: 1864-1880.
4. Chen L#, Liao B#, Qi H, Xie LJ, Huang L, Tan WJ, Zhai N, Yuan LB, Zhou Y, Yu LJ, Chen QF, Shu W, and Xiao S*. (2015) Autophagy contributes to regulation of the hypoxia response during submergence in Arabidopsis thaliana. Autophagy 11: 2233-2246.
3. Chen QF#, Xu L#, Tan WJ#, Chen L, Qi H, Xie LJ, Chen MX, Liu BY, Yu LJ, Yao N, Zhang JH, Shu W, and Xiao S*. (2015) Disruption of the Arabidopsis defense regulator genes SAG101, EDS1, and PAD4 confers enhanced freezing tolerance. Molecular Plant 8(10): 1536-1549.
2. Xie LJ#, Chen QF#, Chen MX#, Yu LJ, Huang L, Chen L, Wang FZ, Xia FN, Zhu TR, Wu JX, Yin J, Liao B, Shi JX, Zhang JH, Aharoni A, Yao N, Shu W, and Xiao S*. (2015) Unsaturation of very-long-chain ceramides protects plant from hypoxia-induced damages by modulating ethylene signaling in Arabidopsis. PLoS Genetics 11(3): e1005143. (封面推荐论文)
1. Xie LJ#, Yu LJ#, Chen QF#, Wang FZ, Huang L, Xia FN, Zhu TR, Wu JX, Yin J, Liao B, Yao N, Shu W, and Xiao S*. (2015) Arabidopsis acyl-CoA-binding protein ACBP3 participates in plant response to hypoxia by modulating very-long-chain fatty acid metabolism. Plant Journal 81: 53-67.
主要科研项目：
近年来承担国家自然科学基金NSFC-RGC联合基金重点项目、区域创新发展联合基金重点项目、国际合作研究项目、面上项目、国家杰出青年科学基金项目、广东省重点研发计划项目等10余项科研课题。
社会兼职
水产动物疫病防控与健康养殖全国重点实验室副主任，广东省热带亚热带植物资源重点实验室主任。兼任广东省植物生理学会副理事长，中国作物学会理事，中国植物学会植物细胞生物学专业委员会委员、分子生物学专业委员会委员、青年工作委员会委员，国际期刊Advanced Biotechnology常务副主编、Journal of Integrative Plant Biology、Frontiers in Plant Science编委等职务。